Most senders think they’re in the clear once an email is marked “delivered.” Delivery status, though, means nothing if your message ends up buried in spam, filtered to promotions, or quietly ignored.
If you're sending at scale or managing multiple email streams, email deliverability best practices aren’t just technical housekeeping. They’re the backbone of your performance. Reputation, infrastructure, authentication, behavioral signals… they all play a role in determining whether your emails make it to the inbox and get read.
This guide goes deeper than surface-level advice.
We’ll walk through the real mechanics of deliverability: what ISPs are watching, how to stay ahead of reputation shifts, what to monitor daily (and what’s a distraction), and what to fix first when things go south. Whether you’re managing transactional sends, lifecycle flows, or cold outreach at volume, this isn’t theory. It’s practical, layered strategy.
Some teams obsess over copy and design but overlook the invisible mechanics driving deliverability. Yes, your subject line and formatting matter—but they’re the tip of the iceberg.
The reality is, most filtering decisions happen before content is even analyzed. ISPs look at your infrastructure, your domain’s history, the sending pattern, and how people interacted with your last few emails. These are all core factors in any set of email deliverability best practices.
Deliverability starts with setup. If your SPF, DKIM, and DMARC records aren’t properly configured, your emails are walking into inboxes without credentials. Even if they slip through, they’re less likely to land in primary folders—and more likely to get flagged on the next send.
Then comes your IP reputation. Shared IPs can get tainted by another sender’s behavior. Dedicated IPs give you more control—but only if you warm them properly. Rapid spikes in volume, sending from multiple domains without history, or ignoring bounce classifications can all quietly erode your deliverability.
Inbox providers care deeply about how their users respond to emails. That’s why two identical emails sent to two different people can have entirely different outcomes.
If someone opens, clicks, and interacts with your emails regularly, future emails from your domain are more likely to land in their primary inbox. If they ignore your emails, or worse, delete them without opening, your sender reputation drops for that individual. This personalization of filtering means global sender stats only tell part of the story.
It also explains why old-school “blasts” no longer work: they flatten nuance, ignore engagement history, and speed up domain fatigue.
Sending more emails doesn’t mean getting better results and certainly doesn’t align with email deliverability best practices built for long-term reputation. In fact, it often means the opposite, especially if those emails hit cold inboxes or disengaged subscribers. The smartest teams know that timing, segmentation, and pacing matter just as much as content.
Instead of treating your list as one big audience, start thinking in layers: Who’s opening? Who’s ignoring? Who used to engage and dropped off? Each group deserves a different approach.
It’s tempting to keep emailing everyone until they unsubscribe. But here’s the tradeoff: every unopened or deleted email chips away at your deliverability.
That doesn’t mean you should immediately purge your list. It means creating a threshold for inactivity—maybe 90 days without an open or click—and suppressing those contacts from regular campaigns. You can always build a re-engagement flow later, but sending to ghost subscribers will drag down your sender score across the board.
Some users want weekly updates. Others prefer one email a month. If your cadence is too aggressive for one segment and too sparse for another, you’ll lose both.
Adaptive cadencing means letting engagement data influence send timing.
If a user is opening and clicking, you might send twice as often. If they haven’t engaged recently, reduce the pace or pause entirely.
Many ESPs offer this in theory—but few execute it well. That’s where infrastructure-level control (like what Senders enables) becomes crucial.
You can’t fix what you’re not tracking—and relying on surface-level metrics like open rates or generic “delivered” statuses won’t cut it. Deliverability issues rarely announce themselves. They creep in slowly, hiding behind good-looking campaign dashboards. That’s why any reliable guide to email deliverability best practices includes ongoing visibility into bounce codes, complaint rates, and throttling signals.
Most platforms delay or dilute key insights. By the time you notice a drop in performance, the damage is already done. Instead, you need direct access to real-time data: bounce classifications, SMTP response codes, ISP-specific delays, complaint spikes. These are the signals that reveal how inbox providers actually see you.
If you’re not set up to monitor this natively, you’re flying blind.
Gmail, Microsoft, and Yahoo offer postmaster tools and complaint reporting. And yes, it’s worth reviewing them. But keep in mind—they’re lagging indicators. By the time Gmail flags your domain with a poor reputation, you’ve probably already been throttled.
Use them to confirm problems, not to detect them. For detection, build your own alerting system or work with platforms that give you real-time visibility into deliverability health.
Quick tip: If you see soft bounce rates increasing week over week—especially with vague response codes like 4.2.1 or 4.4.5—it’s often a sign of temporary ISP filtering. That’s not something most dashboards will surface unless you're looking for it.
Following email deliverability best practices means watching for subtle, early-stage changes before they become performance blockers.Most deliverability issues don’t show up as clear errors. There’s no red alert. Just subtle signs: fewer clicks, odd delays, open rates falling without explanation. When that happens, here’s where to look first.
Check Gmail first—it’s often the canary in the coal mine. Look at recent open rates by domain, not overall. If Gmail opens are falling but others hold steady, chances are you’re landing in Promotions or spam.
Next, pull engagement recency. Are you still emailing contacts who haven’t opened in 3+ months? If so, start suppressing that segment immediately. You’re hurting your sender reputation every time they ignore you.
Not all soft bounces are created equal. Occasional 4xx codes are normal. But if they’re rising—and especially if they cluster around one ISP—you might be facing temporary throttling. This can be caused by volume spikes, engagement drops, or sudden changes in sender behavior.
Start throttling those sends, reduce volume to that domain, and check for any sudden changes in content or cadence.
Don’t rush to switch domains. That’s often the nuclear option—and it usually causes more problems. Instead, pause high-risk sends, isolate segments with high complaint potential, and route carefully.
Subdomain rotation or traffic splitting can help isolate and recover without starting from scratch. It’s about control, not a full reset.
We’ve seen it happen more than once: teams build beautifully written flows, obsess over subject lines, polish every detail—then send to a bloated, disengaged list. And just like that, inbox placement tanks.
If your list hygiene is off, nothing else will work. Not strategy. Not creative. Not timing.
Deliverability starts with knowing who not to email. If someone hasn’t opened or clicked in the last 60–90 days, they’re not just inactive—they’re a liability. These users signal disinterest to ISPs, and repeated sending tells inbox providers that you’re ignoring engagement cues.
Here’s what a proactive list cleaning approach looks like:
Small shifts here make a big difference. List health is one of the fastest ways to improve inbox placement across the board—and one of the most overlooked.
Even experienced teams make deliverability mistakes—not because they don’t know better, but because the issues don’t always show up immediately. The signals are subtle. And by the time something breaks, it’s already hurt your sender score.
Some of these problems are easy to fix. Others are more about long-term process. They’re the kind of avoidable missteps that a strong set of email deliverability best practices is designed to prevent.
Here’s what still trips up senders (and how to spot it early):
A quick note: These issues usually don’t explode all at once. But stack a few together—and your next campaign might ghost half your list before you even notice.
It’s easy to treat email deliverability like a box to tick. Add authentication? Check. Clean the list once? Done. But keeping your emails in inboxes takes more than setup. It takes discipline, ongoing visibility, and a willingness to fix small things before they snowball.
The email deliverability best practices we’ve outlined here aren’t optional—they’re foundational. If you’re managing high-volume sends, every segment, every cadence, every bounce matters. And the teams that treat deliverability as an active system—not a static configuration—are the ones that win.
If you’re ready to stop guessing and start controlling the outcomes of your email program, build smarter infrastructure—or work with someone who already has.
Founded by chef David Chang, Momofuku is a renowned culinary brand with a nation-wide presence, including restaurants and an online store with delicious goods. They ran into an issue with their email sending – high bounce rates and blocked sending.
With hundreds of thousands of people on their email lists eager to stay informed, and an impeccable reputation to uphold, Momofuku wanted to nip this problem in the bud quickly.
Up for coffee with a health kick, sans the jitters? Try Everyday Dose – a brand on a mission to provide coffee lovers with a healthy alternative packed with all kinds of goodies. The Founder, Jack Savage, learned through personal experience that we needed an option that doesn’t lead to a slew of possible side-effects. That’s how this mushroom-based blend with nootropics and collagen protein came to be, helping boost focus, energy, and reduce stress in one go.
The Everyday Dose team prides itself on excellent customer support, in addition to their delicious set of products. So when they spotted DNS propagation issues setting up their customer experience platform, they reached out to Senders to find the best way to sort it out.
Myrina.ai stands out as a trailblazer in empowering women entrepreneurs through technology and a supportive community.
Myrina.ai offers a cutting-edge range of AI-powered SaaS marketing and sales tools that cater specifically to female entrepreneurs and women-led businesses. Myrina.ai enables users to automate marketing and sales, while helping them scale their authentic selves while saving time and boosting conversions. Their Myrina’s Army community fosters a supportive platform that champions female entrepreneurs and their values, empowering them to conquer barriers and achieve their business goals. The company's dedication to providing not only top-notch technological solutions but also a platform for networking and mentorship underscores their commitment to fostering success among women in the entrepreneurial space.
Naturally, they wanted to make sure their email sending infrastructure was set up correctly to protect their reputation and successfully reach their recipients. Our deliverability team worked with the client’s team on:
Sometimes the sheer number of options of any product can be daunting – how on earth do you pick the right one? This is especially true with supplements, as we can find them just about anywhere, but we can rarely understand a third of the ingredients listed. Unlike most, Physician’s Choice provides supplements with pure, potent ingredients that work. No fillers or “proprietary” blends with unidentified ingredients. They do the research, so you don’t have to.
Integrity and transparency are part of their core values, so when their team ran into sending issues, they were referred to Senders.